Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors
alvarez, Cristian
- 1Universidad de La Frontera
- 2University of Granada
- 3Universidad Autonoma de Chile
- 4Universidad Catolica del Maule
- 5Universidad de Santiago de Chile
- 6Universidad de O'Higgins
- 7
- 8Universidad Finis Terrae
- 9Univ St Tomas
- 10Universidad de Antofagasta
- 11Universidad Andres Bello
Journal
Frontiers in Physiology
ISSN
1664-042X
Open Access
gold
Volume
13
The non-responders (NRs) after exercise training have been poorly studied in populations with morbid obesity. The purpose of this study was to determine the NR prevalence after 20 weeks of concurrent training of morbidly obese women with a high or low number of metabolic syndrome (MetS) risk factors. Twenty-eight women with morbid obesity participated in an exercise training intervention and were allocated into two groups distributed based on a high (& GE;3, n = 11) or low number (< 3, n = 17) of MetS risk factors. The main outcomes were waist circumference (WC), fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (Tg), and systolic (SBP) and diastolic (DBP) blood pressure, and secondary outcomes were body composition, anthropometric and physical fitness, determined before and after 20 weeks of concurrent training. NRs were defined as previously used technical error cut-off points for the MetS outcomes. Significantly different (all p < 0.05) prevalences of NRs between the H-MetS vs. L-MetS groups (respectively) in WC (NRs 18.2 % vs. 41.1 %, p < 0.0001), SBP (NRs 72.7 % vs. 47.0 %, p = 0.022), DBP (NRs 54.5 % vs. 76.4 %, p < 0.0001), FPG (NRs 100% vs. 64.8 %, p < 0.0001), and HDL-c (NRs 90.9 % vs. 64.7 %, p = 0.012) were observed. In addition, the H-MetS group evidenced significant changes on&UDelta;SBP (-10.2&PLUSMN; 11.4 mmHg),&UDelta;FPG (-5.8&PLUSMN; 8.2 mg/dl),&UDelta;HDL-c (+4.0&PLUSMN; 5.9 mg/dl), and&UDelta;Tg (-8.8&PLUSMN; 33.8 mg/dl), all p < 0.05. The L-MetS group only showed significant changes in&UDelta;WC (-3.8&PLUSMN; 5.0 cm, p = 0.009). Comparing H-MetS vs. L-MetS groups, significant differences were observed in increment FPG (-5.8&PLUSMN; 8.2 vs. +0.3&PLUSMN; 3.2 mg/dl, p = 0.027), but not in other MetS outcomes. In conclusion, 20 weeks of concurrent training promotes greater beneficial effects in morbidly obese patients with a high number of MetS risk factors. However, the NR prevalence for improving MetS outcomes was significantly superior in these more-diseased groups in SBP, FPG, and HDL-c, independent of their major training-induced effects.
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