A NOVEL NORMULINANE ISOLATED FROM Azorella compacta AND ASSESSMENT OF ITS ANTIBACTERIAL ACTIVITY

San Martin Barrientos, Aurelio Del Carmen; Bacho, M.; Núñez, S.; Rovirosa, J.; Soler, A.; Blanc, V.; León, R.; Olea, A. F.

doi:10.4067/s0717-97072018000304082

A NOVEL NORMULINANE ISOLATED FROM Azorella compacta AND ASSESSMENT OF ITS ANTIBACTERIAL ACTIVITY

San Martin Barrientos, Aurelio Del Carmen

[1];

Bacho, M.

[2];

Núñez, S.

[2];

Rovirosa, J.

[3];

Soler, A.

[4];

Blanc, V.

[4];

León, R.

[4];

Olea, A. F.

[5]

¹
Departamento de Ciencias y Recursos Naturales
²
Universidad de Chile
³
Universidad de Magallanes
⁴
Dentaid Research Center
⁵
Universidad Autónoma de Chile

DOI

10.4067/s0717-97072018000304082

Date Issued

2018

Type

Artículo

Journal

Journal of the Chilean Chemical Society

ISSN

0717-9707

Open Access

gold

Volume

63

Start page

4082

End page

4085

Links

https://arca.umag.cl/handle/123456789/13679

ABSTRACT Phytochemical analysis of Azorella compacta resulted in the isolation of six known diterpenes and one unknown norditerpene using chromatographic methods. The structure of this new compound was established by spectroscopic analysis. The bioactivity of the new compound was assessed against six oral bacteria using a drop test method. A high level of growth inhibition was observed against F. nucleatum and P. gingivalis; however, other species such as V. parvula and A. actinomycetemcomitans were not affected.

azorella compacta

diterpenes

normulinane

yareta

Name

document.pdf

Type

Main Article

Size

301.41 KB

Format

Adobe PDF

Checksum

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